Liver
Albumin / Globulin Ratio
What This Marker Tells Us
Compares albumin, your body's primary transport and antioxidant protein, to globulins, a diverse group including immune antibodies and inflammatory proteins, revealing nutritional status and immune system activation.
Why It Matters
This ratio detects chronic inflammation, immune dysfunction, liver disease, kidney problems, and malnutrition before more obvious symptoms appear. Albumin maintains fluid balance, transports hormones and nutrients, and provides antioxidant protection. Globulins include antibodies fighting infections and inflammatory proteins responding to tissue damage. An imbalanced ratio indicates your body is chronically fighting something like infection, autoimmunity, cancer, or metabolic stress, therefore diverting resources from maintenance and repair.
How to Interpret Your Trends
Low ratios indicate elevated globulins from chronic infection, autoimmune conditions, inflammation, or certain cancers, or low albumin from liver disease, kidney loss, or malnutrition. Typical ratios (1.0-2.5) suggest balanced protein synthesis and controlled inflammation. High ratios may reflect excellent health, low globulin from immunodeficiency, or certain genetic conditions. Trends matter more than single measurements.
What Influences This Marker
Chronic infections, autoimmune diseases, inflammatory conditions, and persistent stress elevate globulins. Inadequate protein intake, liver disease, kidney disease, and malabsorption lower albumin. Intense training without adequate recovery increases inflammatory globulins. Balanced nutrition, stress management, adequate sleep, and treating underlying conditions normalize this ratio.
How Your Team Uses It
Your team uses A/G ratio trends to assess recovery capacity, identify hidden inflammation, and optimize nutrition protocols. Declining ratios prompt investigation of gut health, immune function, and training load. It guides anti-inflammatory interventions and protein intake recommendations.
Related Signals We Also Review
Total protein, albumin, globulin, CRP, ESR, complete blood count, liver enzymes, and kidney function markers complete the inflammation and nutritional assessment.